alarming occurence of esophageal cancer in Balochistan

To evaluate the prevalence, geographical features and disease characteristics of Cancer of Esophagus in patients registered at Centre for Nuclear Medicine and Radiotherapy [CENAR]. From January 1991 to December 2001 832 cases of esophageal cancer were seen at CENAR Hospital Quetta. Only cases confirmed by Histopathology and for whom the esophagus was the primary site of tumor were included in the study. The mean age of the patients was 50 + 13year]. The geographical background and disease characteristics were elaborated, by calculating statistical ratios and percentages of various demographic variables, in different subgroups of patients. Cancer of esophagus is 3 rd commonest tumor [11.3% of total registered cases] and on average, the annual proportion of esophageal cancer constitutes a figure of 11 cases per hundred patients diagnosed at CENAR Hospital. It is third common tumor in male and 4 th common in female, with Male to female ratio of 1.37. It is about 1.33 times more common in Balochistan than in Afghanistan. Naswar and beetle nut chewing [31%], malnutrition [56%] and Alcohol [13%] were among the common risk factors present in this study population. About 90% of the cases were of Squamous cell variety and 85% of the patients were diagnosed when disease has progressed to stage 3/4 and upto 60% cases involve lower third of esophagus. Forty percent of the patients were in 4th decade of life at time of diagnosis. The areas that surround CENAR Hospital in Balochistan Province seem to be a high-risk belt for esophageal cancer. It is also common in Afghanistan and Peshawar. Naswar and beetle nut chewing along with malnutrition and alcohol might be important contributory risk factors

Diagnosis of oral squamous cell carcinoma of fine needle aspiration cytology

The purpose of this study was to determine the possibility of using fine needle aspiration cytology [FNAC] as a primary diagnostic test in oral squamous cell carcinoma. The sample consisted of twenty cases of white and red lesions and forty cases of squamous cell carcinoma. FNAC and conventional incision biopsy was done on all the cases. A cytological and histopathological correlation was made. The result showed that both true positive and false negative result were obtained. In oral squamous cell carcinomas, 88.3% were true positive. 10% of false negative results were obtained in the white and red lesions. The overall positive correlation was 50%. The present study indicates that FNAC can be used as a reliable diagnostic test for oral squamous cell carcinoma

Partial Anodontia

A severe case of partial anodontia male aged, 24 is reported with the complaint of speech and masticatory function prevailing with difficulties. He has been successfully and conservatively treated with full upper and lower overlay dentures. Aesthetics, speech and masticatory function have been improved with no deterioration in oral health